Bitler and claudin-4
WebICC/IF image of ab53156 staining Claudin 4 (green) in MCF7 (Human breast adenocarcinoma cell line) cells. The cells were fixed in 4% formaldehyde (10 minutes) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1 hour to permeabilize the cells and block non-specific protein-protein interactions. The … WebMar 18, 2024 · The role of claudins in maintaining cell barrier as well as small ions and neutral solutes selective transport is crucial: experimental claudins knockout models lacking CLDN1 and CLDN5 are lethal [14,15].Overexpression of claudin-1, claudin-4, claudin-5, and claudin-7 increase transepithelial resistance (TER), whereas claudin-2 and claudin …
Bitler and claudin-4
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WebMar 11, 2002 · Distinct from claudin-1, claudin-4 was distributed mainly in the second/third layers of stratum granulosum (a). Claudin-4 was also concentrated at the occludin-positive lines circumscribing granular cells (arrowhead) (b). SC, stratum corneum. The broken line represents the dermis/epidermis border. Bars, 20 μm. WebSep 1, 2015 · Neville MC, Webb PG, Baumgartner HK, Bitler BG. Claudin-4 localization in epithelial ovarian cancer. Heliyon. 2024 Oct; 8(10):e10862. PMID: 36237976. ... Ovarian …
WebAug 19, 2009 · In addition to claudin-4, the levels of most claudin decreased significantly with age, except for claudin-2 and -7 where the decrease was observed only in females . Again, when the male and female mice were examined as group at multiple points, most claudins exhibited a trend toward being expressed at lower levels in aged animals ( … WebMichael Koval, in Lung Epithelial Biology in the Pathogenesis of Pulmonary Disease, 2024. 1.4.2.2 Claudin-4. Claudin-4 also is prominently expressed throughout the lung …
WebAug 15, 2005 · Abstract. Claudin proteins form a large family of integral membrane proteins crucial for tight junction formation and function. Our previous studies have revealed that claudin-3 and claudin-4 proteins are highly overexpressed in ovarian cancer. To clarify the roles of claudins in ovarian tumorigenesis, we have generated human ovarian surface … WebBenjamin Bitler, PhD, is a faculty member in the Division of Reproductive Sciences. His research interests include Ovarian cancer, Wnt signaling, and epigenetics. ... Ovarian …
WebJul 7, 2024 · In addition, some data have demonstrated that claudin delocalization contributes to cancer hallmarks. For instance, activated ephrin receptor A2 phosphorylates the tyrosine residue of claudin-4, decreasing its association with ZO-1 and leading to claudin-4 accumulation in the cytoplasm, which decreases the integration of claudin-4 …
Web1 Claudin-4 Localization in Epithelial Ovarian Cancer Margaret C. Neville*, Patricia G. Webb, Heidi K. Baumgartner, Benjamin G. Bitler Margaret C. Neville, (Corresponding … bing classic quizWebPTHR12002:SF89 CLAUDIN-4 1 hit; PRINTS. PR01077 CLAUDIN; PR01379 CLAUDIN4; PROSITE. View protein in PROSITE; PS01346 CLAUDIN 1 hit; Pfam. View protein in Pfam; PF00822 PMP22_Claudin 1 hit; MobiDB. bing civil war quizWebSep 24, 2024 · The increase of claudin-4 in rat colon after chronic DMH exposure was consistent with the acute effect of DMH on IPEC-J2 cells, which may indicate an essential role of this protein in colorectal cancer development. ... P.G.; Galimanis, C.E.; Bitler, B.G.; Behbakht, K.; Baumgartner, H.K. Ovarian Tumor Cell Expression of Claudin-4 Reduces ... bing classical composers yyyWebJan 13, 2014 · Claudin-4 is a tight-junction-associated protein that is expressed in most epithelial cells but is absent in mesothelial cells. 12 Immunohistochemistry for claudin-4 … cytonn coding schoolWebClaudin-4 was detected at ~27 kDa using Claudin-4 Mouse Monoclonal Antibody (Product # 32-9400) at 1-3 µg/mL in 2.5 % skim milk for 3 hours at room temperature on a rocking platform. Goat Anti-Mouse IgG - HRP … bing clashWebCancer Cytopathol. 2014 Apr;122(4):299-306. 2. Ohta Y, Sasaki Y, Saito M, et al: Claudin-4 as a marker for distinguishing malignant mesothelioma from lung carcinoma and serous adenocarcinoma. Int J Surg Pathol. 2013 Oct;21(5):493-501. 3. Ordonez NG: Value of claudin-4 immunostaining in the diagnosis of mesothelioma. Am J Clin Pathol. 2013 May ... bing classic games quiz 2010WebBrief Fact Summary. After a probate court disapproved a will in which Bull (Defendant) was named as a beneficiary, allowing Calder (Plaintiff)) to inherit instead, the state legislature … cytonn company