WebNoun 1. one shot - a charge of ammunition for a single shot round, unit of ammunition ammo, ammunition - projectiles to be fired from a gun Based on WordNet... One shot - … WebOct 26, 2024 · In addition, influenza viruses mutate constantly. That's one reason why creating a single flu shot for ongoing protection has been challenging. When viruses mutate, the antigens change. This means if you have antibodies that worked against a previous strain, they won't work against the new one.
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