Lamp1 自噬溶酶体

Author: scew

August undefined, 2024

TīmeklisThe lysosomal membrane proteins LAMP-1 and LAMP-2 are estimated to contribute to about 50% of all proteins of the lysosome membrane. Surprisingly, mice deficient in …

Different localization of lysosomal-associated membrane …

Tīmeklis2024. gada 3. sept. · Our study demonstrates that a significant portion of LAMP1-labeled organelles do not contain detectable lysosomal hydrolases including cathepsins D … TīmeklisLAMP1抗体 [GT25212] (GTX634336) GeneTex中国官方网站 Back 一抗二抗抗体套装 ELISA抗体对和试剂盒同型对照蛋白质和多肽切片裂解液血清和血浆试剂研究试剂盒研究工具 Back 肿瘤研究肿瘤标记神经科研细胞生物学代谢科研表观遗传学心血管免疫学发育研究细胞标记信号通路研究传染性疾病研究细胞器标记斑马鱼科研兽医 … pry tool for phone

【精品导读】我从未见过如此天秀的自噬研究 - 知乎

Tīmeklis2005. gada 15. nov. · High levels of LAMP1-GFP overexpression elicited aberrant aggregation of late endocytic organelles, a phenomenon that probably involved formation of anti-parallel dimers of LAMP1-GFP as it was not observed in cells expressing comparable levels of a non-dimerizing mutant variant, LAMP1-mGFP. To … TīmeklisTo investigate its role during EAE, we inactivated Lamp1 in astrocytes using a lentivirus that co-expresses Gfap-driven CRISPR–Cas9 and either a Lamp1-targeting or a non-targeting single-guide ... Tīmeklis再次探讨LAMP1作为神经系统中降解自噬-溶酶体细胞器的标志物溶酶体充当宏自噬/自噬和胞吞成分的降解中心，因此维持了神经元存活和功能必不可少的细胞稳态。 … prydgear

LAMP1/CD107a is required for efficient perforin delivery to lytic ...

细胞器标志物丨LAMP1抗体 - 知乎 - 知乎专栏

Tīmeklis译：PLA2G4A/cPLA2介导的溶酶体膜损伤导致脑外伤后的自噬抑制和神经变性 Highlights： 1、PLA2G4A是脑外伤后小鼠大脑皮质溶酶体膜通透性（LMP）的主要贡 … TīmeklisDifferential distribution patterns of LAMP1 and cathepsin D in adult mature DRG neurons in vivo. (A and B) Representative images (A) showing partial colocalization of LAMP1 and cathepsin D in DRG axon bundles from adult mice at P120. Mice were perfused with 50% Bouin’s solution, and DRGs were isolated for … pry\\u0027s towing and automotive slippery rock paTīmeklis2024. gada 6. janv. · LAMP1 has a molecular mass of between 90 and 120 kDa, and is heavily glycosylated with a large number of N-glycans and some O-glycans (Fukuda 1991; Eskelinen et al. 2003 ). The N-glycans of LAMP1 and LAMP2 protect against proteolytic degradation in lysosomes (Kundra and Kornfeld 1999 ). pry\u0027s towing butler pa

"Tīmeklis2013. gada 6. jūn. · LAMP1 is important for perforin trafficking to the lytic granules and granule movement. Abstract Secretory lysosomes of natural killer (NK) cells, containing perforin and granzymes, are indispensable for NK-cell cytotoxicity because their release results in the induction of target-cell apoptosis. " - Lamp1 自噬溶酶体

Lamp1 自噬溶酶体

Characterization of LAMP1-labeled nondegradative lysosomal and …

Tīmeklis摘要：溶酶体相关膜蛋白LAMP1 (lysosome-associated membrane protein 1)是主要存在于溶酶体膜上的一种高度糖基化的糖蛋白,参与细胞内多种生理和病理过程.近年有 … Tīmeklislamp1质量控制：＞95%(还原性sds-page) lamp1制剂：冻干品 lamp1保存：冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。复溶蛋白溶液可在4～7℃保 …

Did you know?

Tīmeklis2024. gada 18. jūl. · LAMP1 (lysosomal associated membrane protein 1) and LAMP2 are distributed among autophagic and endolysosomal organelles. Despite … TīmeklisLAMP1. Lysosomal-associated membrane protein 1 ( LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a ( C luster of D ifferentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, band 4 (13q34).

TīmeklisLAMP-1 Antibody (H4A3) is an IgG 1 κ mouse monoclonal LAMP-1 antibody (also designated LAMP1 antibody or CD107a antibody) that detects the LAMP-1 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM. LAMP-1 Antibody (H4A3) is available as both the non-conjugated anti-LAMP-1 antibody form, as well as … Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, … Skatīt vairāk Residing primarily across lysosomal membranes, these glycoproteins consist of a large, highly glycosylated end with N-linked carbon chains on the luminal side of the membrane, and a short C-terminal tail exposed to the Skatīt vairāk LAMP1 and LAMP2 glycoproteins comprise 50% of all lysosomal membrane proteins, and are thought to be responsible in part for maintaining lysosomal integrity, pH and catabolism. … Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and … Skatīt vairāk LAMP1 expression on the surface of tumor cells has been observed for a number of different cancer types, particularly in highly metastatic … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • LAMP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an … Skatīt vairāk

TīmeklisPA1-654A detects Lamp1 from human samples. PA1-654A has been successfully used in immunofluorescence and Western blotting procedures. In immunofluorescence procedures, this antibody … Tīmeklis2024. gada 27. jūl. · LAMP1，即溶酶体相关膜蛋白1，又称CD107a、是单层膜结构的囊泡状细胞器，内含多种酸性水解LAMP-A、lgp120，最早于1985年由Chen等 [10]和 …

Tīmeklis2024. gada 2. jūl. · Neuritic plaques in Alzheimer’s disease (AD) brains refer to β-amyloid (Aβ) plaques surrounded by dystrophic neurites (DNs), activated microglia and reactive astrocytes. Most recently, we showed that DNs form sequentially in three layers during plaque growth. Although lysosomal proteins such as LAMP1 are found …

Tīmeklis自噬是一种溶酶体介导的降解系统，是一种进化上保守的途径，用于循环利用细胞内容物，清除聚集的蛋白质、受损的细胞器和入侵的病原体 (如病毒和细菌)，以维持正常的 … pry\u0027s deer processingTīmeklisLAMP1 - lysosomal associated membrane protein 1 Gene 基因蛋白疾病直系同源中文名称：溶酶体相关膜蛋白 1 种属: Homo sapiens 同用名: LAMPA; CD107a; LGP120 基因 ID: 3916 基因类型: protein coding 关于 LAMP1 Cytogenetic location: 13q34 Genomic coordinates (GRCh38): 13:113,297,239-113,323,672 (from NCBI) This gene has 3 … pry tool setTīmeklis2024. gada 28. sept. · 自噬体最终与溶酶体融合，或与内体和溶酶体融合，形成自噬溶酶体并完成封闭成分的降解。. 降解后，通过溶酶体重组产生新的溶酶体，其特征是管 … pry\\u0027s towing butler pa